[CHELATEXX for Autism Spectrum Disorder ]

Excess Ammonia in Autism

tacanow.org/family-resources/excess-ammonia-in-autism

" It is suggested that in patients with autism, the diseased intestines generate more ammonia than the liver can clear at first pass which results in ammonia entering the brain"

"In this study, the concentration of ammonia in stool was significantly greater in ASD participants than in controls" www.pubmed.gov/22535281

Detoxification and Autism

tacanow.org/family-resources/detoxification-and-autism/

"It has been shown that kids with Autism have impaired detoxification. One in six children has a neurodevelopmental disability" www.pubmed.gov/20628438 www.pubmed.gov/32006375

Use Binders if Necessary (recommended)

: Activated Charcoal

: Vitamin C

: Modified Citrus Pectin

Autistic-like findings associated with a urea cycle disorder in a 4-year-old-girl

www.pubmed.gov/15798789

serum ammonia level 144 micromoles/l (normal under 50 micromoles/l

"The patient's protein intake was restricted, and she was treated with sodium benzoate and arginine"

"After 1 year of treatment, the autistic-like findings and hyperactivity were no longer apparent"

Assessment of Amino Acids, Ammonia and Oxidative Stress Among Cohort of Egyptian Autistic Children

www.pubmed.gov/32021195 (Full text)

Table 5 Autism Spectrum Disorder (54 patients) median serum ammonia 189 ug/dl (63 micromol/l)

Cohort Controls (64 patients) median serum ammonia 134 ug/dl (44 micromol/l)

p value 0.001 (significant < 0.01)

"Dysregulated amino acid metabolism, high ammonia and oxidative stress were prevalent among autistic children and should be considered in autism management"

Biomarker

References :

1. Effects of gut-microbial-based treatments on gut microbiota, behavioral symptoms, and gastrointestinal symptoms in children with autism spectrum disorder: A systemic review

www.pubmed.gov/33198044

2. Gastrointestinal involvement of autism spectrum disorder: focus on gut microbiota

www.pubmed.gov/33356668

3. The Human Gut Microbiome as a Potential Factor in Autism Spectrum Disorder

www,pubmed.gov/35163286

4. Targeting gut microbiome: A novel and potential therapy for autism

www.pubmed.gov/29277311

5. Gut microbiota in autism and mood disorders

www.pubmed.gov/26755882

6. The microbiota-gut-brain axis and its potential therapeutic role in Autism Spectrum Disorders

www.pubmed.gov/26964681
7. Fecal Microbiota Transplantation in Autism Spectrum Disorder

www.pubmed.gov/36544550

8. Fecal Microbiota Transplantation Relieves Gastrointestinal and Autism Symptoms by Improving the Gut Microbiota in an Open-Label Study

www.pubmed.gov/34737978